General Prevention
- Progestogens: Currently, there is no evidence that routine use of oral or IM progestogens prevents miscarriage in early to mid-pregnancy. However, there is some evidence that women with a history of recurrent miscarriage may benefit from this type of treatment (1)[A]. Likewise, there is no evidence that progesterone has utility as a treatment for threatened abortion (2)[A].
- Immunotherapy: There is no current evidence to support use of immunotherapy in patients with a history of recurrent miscarriage (3)[A].
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