5-Minute Clinical Consult

Irritable Bowel Syndrome

Irritable Bowel Syndrome was found in 5-Minute Clinical Consult which helps you diagnose, treat, and follow up on over 900 medical conditions seen in everyday practice.

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Basics

Description

  • A condition characterized by:
    • Chronic abdominal pain associated with:
      • Alteration in bowel habits AND
      • Absence of organic pathology.
  • May be characterized as diarrhea-predominant or constipation-predominant; or may alternate between diarrhea and constipation.
  • Synonym(s): Spastic colon; Irritable colon

Epidemiology

Irritable bowel syndrome (IBS) accounts for up to 50% of GI visits in some practices:

  • Second to upper respiratory infection as cause for lost workdays
Prevalence
  • Estimated to be ~15% of the population of North America:
    • However, only 15% of these patients actually seek medical attention.
  • Predominant age: Teens to late 20s:
    • If age >50 years, consider other diagnoses.
  • Predominant sex: In the US, Female > Male (2:1)

Risk Factors

  • Other family members with similar GI disorder
  • History of childhood sexual abuse
  • Sexual/Domestic abuse in women
  • Depression
  • Can occur after an infectious colitis (1)

Pregnancy Considerations
No risk to mother or fetus

Genetics
Unknown, but more common in families of IBS patients

General Prevention

See “Diet.”

Etiology

  • The etiology is unknown, but patients demonstrate intestinal motility abnormalities with enhanced sensitivity to visceral stimuli.
  • The trigger may be luminal or environmental.

Commonly Associated Conditions

  • Migraine
  • Urinary frequency and urgency
  • Fibromyalgia
  • Dyspareunia
  • Depression

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