Select 5-Minute Pediatrics Topics

Common Variable Immunodeficiency

Common Variable Immunodeficiency was found in Select 5-Minute Pediatrics Topics which helps you diagnose, treat, and follow up on over 900 medical conditions seen in everyday practice.

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Description

  • A heterogeneous immunodeficiency syndrome characterized by:
    • Hypogammaglobulinemia
    • Recurrent infections
    • A wide spectrum of immunologic abnormalities, including autoimmune disease, inflammatory conditions, and the development of lymphomas
  • A common primary immunodeficiency
  • Other terminology for this disease includes:
    • Acquired hypogammaglobulinemia
    • Adult-onset hypogammaglobulinemia
    • Dysgammaglobulinemia
    • Common variable hypogammaglobulinemia
  • Diagnosis of exclusion, requiring variable reduction in one or more immunoglobulin classes (IgG, IgA, and/or IgM), impaired specific antibody responses, and in some cases reduction of B cell number

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