Division of Ophthalmology, Southern Illinois University School of Medicine, Springfield 62794-9230.
SourceAnn Ophthalmol 1990 Feb; 22(2)
Two black women had bilateral anterior and posterior uveitis, nonrhegmatogenous retinal detachments, pleocytosis, headaches, dysacousis, and alopecia. These patients with Vogt-Koyanagi-Harada (VKH) syndrome improved clinically while they were pregnant after the discontinuation of corticosteroid treatment. They developed recurrent symptoms and findings after termination of their pregnancies. We speculate that changes in immunity and humoral constituents during pregnancy account for their remissions. It is important to assess the menstrual history and to avoid pregnancy before initiating steroid treatment for VKH syndrome.
MeshAdultFemaleFluorescein AngiographyFundus OculiHumansPregnancyPregnancy ComplicationsRecurrenceUveitisUveomeningoencephalitic SyndromeVisual Acuity
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