MEDLINE Journals

    Effect of water temperature on diuresis-natriuresis: AVP, ANP, and urodilatin during immersion in men.

    Authors
    Nakamitsu S, Sagawa S, Miki K, et al. 
    Institution

    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.

    Source
    J Appl Physiol 1994 Oct; 77(4) :1919-25.
    Abstract

    Effects of water temperature on diuresis, natriuresis, and associated endocrine responses during head-out immersion were studied in eight men (23.4 +/- 0.3 yr) during four 5-h experimental conditions: air control at 28 degrees C and immersion at 34.5 degrees C [thermoneutral (Tnt)], 36 degrees C [above Tnt (aTnt)], and 32 degrees C [below Tnt (bTnt)]. Esophageal temperature decreased by approximately 0.4 degrees C in bTnt and increased by approximately 0.5 degrees C in aTnt. Cardiac output increased by approximately 80% in aTnt and approximately 40% in bTnt while thoracic impedance, an index of central blood pooling, decreased by 7.5 omega in bTnt (NS vs. Tnt) and 8.8 omega in aTnt (P < 0.05 vs. Tnt and bTnt). Total peripheral resistance decreased at all temperatures (50% in aTnt, 20% in bTnt). Urine flow and Na+ excretion increased by sixfold in bTnt and Tnt but by only threefold in aTnt. Creatinine clearance was unchanged while osmolal clearance (but not free water clearance) increased two-fold with all immersions. Plasma atrial natriuretic peptide (ANP), urinary urodilatin, and urinary guanosine 3',5'-cyclic monophosphate increased while plasma renin activity, aldosterone, and arginine vasopressin (AVP) decreased similarly at all temperatures. bTnt did not potentiate diuresis by selective attenuation of AVP. The overall natriuretic response exhibited a higher correlation with urodilatin (r = 0.45, P < 0.001) than with ANP (r = 0.26, P < 0.01).(
    ABSTRACT TRUNCATED AT 250 WORDS)

    Mesh
    Adult
    Arginine Vasopressin
    Atrial Natriuretic Factor
    Body Temperature
    Diuresis
    Electrocardiography
    Hemodynamics
    Humans
    Immersion
    Male
    Natriuresis
    Norepinephrine
    Peptide Fragments
    Renin
    Sodium
    Temperature
    Water
    Language

    eng

    Pub Type(s)
    Clinical Trial Comparative Study Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.
    PubMed ID

    7836219

    Content Manager
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