| Browse by Title AAP/AAFP guideline for acute otalgia in children AAP Practice Guideline: Delaying feeding does not prevent atopy ABCD2 score not reliable for stroke prediction after TIA ABCD rule predicts 7- and 30-day stroke risk in pts with TIA ABCD score predicts 7 day stroke risk in patients with TIA Abnormal nuchal translucency does not = abnormal child About 1 in 4 obese children with acanthosis nigricans have impaired glucose control Abx for drained skin abscesses may decrease new lesions in adults Abx in patients with uncomplicated diverticulitis (limited evidence) ACC/AHA: Fewer patients require prophylaxis for endocarditis Accelerated care decreases length of stay in joint replacement surgery Accelerated protocol identifies chest pain patients at low risk for major cardiac events Access to free LARC associated with decreased risk of unintended pregnancy ACE = ARB, but ACE + ARB worsens renal outcomes (ONTARGET) ACE = ARB for secondary CV prevention; combination worse (ONTARGET) ACE inhibitor + ARB = no benefit and increased risk ACE inhibitor preferred over ARB in patients with ischemic heart disease ACE inhibitors effective in CAD without CHF Acellular pertussis efficacy wanes within 5 years after last dose Acetaminophen=celecoxib in DJD Acetaminophen in normal doses safe in children ACL reconstruction not necessary for good clinical outcome ACP Guideline: Intensive insulin therapy not recommended for ICU patients ACP Guideline: Universal VTE prophylaxis not recommended for hospitalized medical and stroke patients ACP guidelines on screening for colon cancer ACS risk similar with normal ECG performed during presence or absence of chest pain Acupuncture better than sham for neck pain Acupuncture effective for chronic shoulder pain Acupuncture effective for long-term back pain relief Acupuncture effective for some with chronic prostatitis Acupuncture improves fibromyalgia symptoms Acupuncture improves in vitro pregnancy rates Acupuncture ineffective for Alzheimer's dementia Acupuncture ineffective for hot flashes Acupuncture may have value in treating GERD Acupuncture may help some people quit smoking Acupuncture may not be effective as a pain reliever Acupuncture more effective than usual care for osteoarthritis Acupuncture possibly effective for ulcerative colitis Acupuncture reduces post-op knee pain Acute migraine: prochlorperazine better than sumatriptan Acute-onset visual floaters and flashes and the risk for retinal detachment Acute pain relief from ibuprofen >= acetaminophen-codeine for extremity injury in kids Adding clopidogrel worsens outcomes following lacunar stroke Adding MTX to sulfasalazine better for RA (MASCOT) Adding steroids improves outcomes in severe Kawasaki disease (RAISE) Adding tiotropium of little benefit in asthma Adenoidectomy does not decrease respiratory tract infections in children ADHD drugs do not increase serious CV events in children and young adults ADHD medications not associated with increased risk of CVD Adjunctive antidepressants not effective for depression in bipolar disorder Adjuvant increases efficacy of influenza vaccine in infants and children Adjuvant radiation for stage I endometrial cancer: less local recurrence, no survival benefit Adolescents and young adults with microscopic hematuria at increased risk of ESRD Adult circumcision prevents HIV transmission in sub-Saharan African men Adult survivors of childhood cancer at increased risk of subsequent cancer Adults with both anxiety and depression respond poorly to treatment After 15 years, 50% of patients with optic neuritis developed MS (ONTT) After colonoscopy, 1.3% have major adverse events and 33% have minor adverse events After surviving in-hospital CPR to discharge, 60% of elderly alive at 1 year, 44% at 3 years Aggressive early tx after TIA/minor stroke improves outcomes (EXPRESS) Aggressive increase in Hgb does not improve QOL Aggressive treatment of asymptomatic GERD does not improve asthma Alcohol screening tool effective in Iding patients at higher risk for postop complications Alemtuzumab more effective than interferon for multiple sclerosis Alendronate therapy unnecessary for most women after 5 years Alexander technique reduces low back pain disability Alfuzosin (alpha-agonist) not effective for chronic prostatitis-chronic pelvic pain Aliskiren worsens outcomes in high-risk diabetics All diets work equally poorly Allergic rhinitis associated with increased risk of bronchial hyperreactivity (ECRHS) Aloe vera gel effective for oral lichen planus Aloe vera not effective for irritable bowel syndrome Alpha-blocker or nifedipine may help pass kidney stones American Pain Society guideline for low back pain Amitriptyline effect on QOL in teens with IBS is equivocal Amox-clavulanate during COPD exacerbations decreases Sx and delays subsequent exacerbations Amoxicillin-clavulanate effective for AOM in kids younger than 3 years Amoxicillin-clavulanate effective for wet cough lasting >3 weeks in kids Amoxicillin still ineffective for acute bronchitis, even in HIV patients Androgen deprivation therapy associated with increased risk of fracture, DM, CVD death Androgen deprivation therapy does not increase risk of CV death in men with prostate cancer Angled insulin insertion with 6-mm needle best for children with T1DM Annual conventional cytology most cost-effective for surveillance after CIN treatment Annual mammography starting at 40 doesn't lower breast CA mortality Annual rupture rate <= 0.5% for aneurysms 3 to 6 mm Annual screening chest x-ray does not reduce lung cancer mortality An omega-3 fatty acid = placebo in Huntington disease Antenatal corticosteroids don?t reduce respiratory morbidity in near-term infants Antenatal magnesium neuroprotective for premies Antiandrogens effective for hirsutism, better than metformin Antibiotic prophylaxis ineffective in vesicoureteral reflux Antibiotic prophylaxis may not decrease risk of recurrent UTI in children Antibiotic prophylaxis promising for anal sphincter repair Antibiotic prophylaxis to prevent UTI effective for high-risk children Antibiotics and nasal steroids of little/no benefit for acute sinusitis Antibiotics do not improve outcomes after IandD of skin abscess Antibiotics for conjunctivitis decreases symptom duration Antibiotics for URIs reduce complications (but not enough to matter) Antibiotics in first year of life associated with later asthma Antibiotics reduce mortality in children with severe acute malnutrition Antibiotics slightly effective for purulent rhinitis Antibiotics slightly increase risk of childhood asthma Anticholinergics, pelvic floor muscle exercises improve urinary incontinence in women Anticholinergics of greater benefit in COPD treatment Anticoagulation ineffective for recurrent miscarriage Anticoagulation reversal with vitamin K doesn't reduce bleeding Anticoagulation self-monitoring and self-management is a safe option Antidepressants helpful in chronic rheumatic and other pain disorders Antidepressants of uncertain effectiveness in patients with depression + dementia Antidepressants only modestly effective for adolescent depression Antihypertensive therapy beneficial for patients with BP < 140/90 and history of CVD Antioxidants, CoQ ineffective for patients with Alzheimer disease Antioxidants don't prevent colorectal cancer Antioxidants do not prevent macular degeneration Antioxidants may increase mortality Antiplatelet agents prevent preeclampsia Antipsychotic drugs more effective than mood stabilizers in acute mania Antiretroviral regimens prevent HIV-1 transmission during breastfeeding Antiretroviral treatment of mother or infants effective during breastfeeding Antithrombotic therapy after stent in patients already using anticoagulant Antiviral medication exposure safe in first trimester of pregnancy Antivirals can prevent influenza but treatment of symptoms is less impressive Antivirals have a small benefit in children AOM wait-and-see treatment without Rx decreases antibiotic use Apixaban increases bleeding with no benefit in high-risk patients with ACS Apixaban reduces stroke and embolism more than aspirin in A fib Apixaban slightly more effective and safe than warfarin, but more expensive Apolipoprotein levels no better than standard methods to evaluate CVD risk A PPI test does not improve diagnosis of GERD Applied behavior intervention = standard care in autism A primary care register for high-risk asthma patients prevents hospitalizations ARBs and ACE inhibitors prevent A fib ARBs reduce BP in prehypertensive patients ARB treatment of high CV risk patients ARDS prognosis A restriction diet will benefit some children with ADHD ASA: not for primary prevention ASA+dipyridamole better than ASA for cerebral ischemia (ESPRIT) ASA effective in secondary prevention of vascular disease, uncertain in primary prevention ASA of limited benefit in patients with diabetes ASA prevents colorectal adenomas Asking "Is there something else?" decreases patients' unmet concerns Asking about suicide doesn't trigger suicidal ideation Ask-tell-ask approach to discussing prostate cancer screening As needed steroid + beta-agonist works well in mild persistent asthma Aspirin + dipyridamole = clopidogrel for recurrent stroke prevention (PROFESS) Aspirin = enoxaparin for prevention of recurrent miscarriage Aspirin dose >81mg daily not beneficial for secondary prevention of CVD Aspirin following anticoagulation therapy prevents recurrent VTE (ASPIRE) Aspirin may prevent cancer in carriers of hereditary nonpolyposis colon cancer (CAPP2) Aspirin prevents colon cancer Aspirin prevents recurrent venous thromboembolism Aspirin prevents vascular events in patients with PAD Aspirin reduces cancer death and all-cause mortality Aspirin use after diagnosis of colon cancer reduces mortality Assessment of geriatric hospital patients: ltd data, ltd effect on outcomes Asymptomatic gallstones rarely lead to cholecystectomy and may go away Atkins equally or more effective for weight loss in premenopausal women Atomoxetine better than placebo but not uniformly effective in young children ATP-III more efficient than JUPITER Atrial fibrillation recurrence higher with episodic treatment with amiodarone Atypical antipsychotics minimally effective, poorly tolerated in AD Atypical antipsychotics worsen cognition in Alzheimer?s (CATIE-AD) Autism not linked to thimerosol in vaccines Autistic disorder symptom treatments have limited evidence Automated blood pressure more accurate in the office Azelaic acid effective for papulopustular rosacea Azithromycin 1% minimally better than placebo for acute conjuctivitis Azithromycin associated with increased risk of CV death Azithromycin at least as effective as doxycycline for PID Azithromycin of questionable benefit given daily for COPD Azithromycin prevents bronchiectasis exacerbations in adults without cystic fibrosis (EMBRACE)
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