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Dabigatran associated with increased risk of coronary events
Dabigatran cost-effective for AF prophylaxis in some patients, not others
Dabigatran reduces risk of stroke and embolism in patients with AF
Dabigatran safe and effective for VTE
Daily cranberry juice does not reduce risk of UTI in pregnancy
Daily multivitamins do not reduce major CV events in men and do not affect mortality
Daily multivitamins have minimal, if any, effect on preventing cancer in men and do not affect mortality
Daily probiotic with Lactobacillus casei reduces upper RTI duration in elderly
Dalteparin = unfractionated heparin for ICU DVT prophylaxis
Dapoxetine slightly improves premature ejaculation
Dapsone gel effective for acne vulgaris treatment
Darbepoetin alfa minimally effective, increases stroke risk in diabetic nephropathy
Day 1 and day 2 postpartum discharge after planned cesarean have similar outcomes
D-dimer can identify high-risk group for extended anticoagulation (PROLONG)
D-dimer vs ultrasound for DVT: use prediction rule
Decision rule identifies kids at low risk of appendicitis
Decreased hospital LOS not associated with increase in 30-day readmission rates
Decrease in breast CA after WHI not caused by mammography changes
Decreasing systolic BP to 130 or lower improves outcomes (CARDIO-CIS)
Deep brain stimulation better than best medical therapy for Parkinson disease
Deep-brain stimulation effective for severe PD
Delayed antibiotics does not reduce long-term reconsultation
Delayed cord clamping improves infant's iron status at 4 months
Delayed cord clamping in full-term infants reduces risk of anemia
Delayed hemorrhage extremely rare following minor head injury
Delayed prescription for AOM reduces unnecessary antibiotics
Delayed-release doxylamine + pyridoxine effective for emesis in pregnancy
Dementia treatments minimally effective
Denosumab reduces fracture risk better than placebo (FREEDOM)
Depression screening effective only with follow-up: USPSTF
Depression screening tests in hospitalized elders only modestly reliable
Dexamethasone + epinephrine more effective for bronchiolitis
Dexamethasone does not prevent migraine recurrence
Dexamethasone does not provide clear benefit in bacterial meningitis
Dexamethasone may prevent headache recurrence after treatment of acute migraine
Dexamethasone not effective for bronchiolitis
Dexamethasone reduces LOS in patients with community-acquired pneumonia
Dextrose injection effective for Osgood-Schlatter disease
DHA does not slow cognitive and functional decline in Alzheimer disease
DHEA, testosterone not effective in aging patients
Diabetes alone is NOT a coronary risk equivalent to a history of myocardial infarction
Diabetes and level of control don't predict outcomes after knee replacement
Diabetes no longer a specific indication for ASA use
Diagnostic accuracy of different stress testing modalities varies for detecting CAD
Diagnostic certainty for type of stroke requires neuroimaging
Diet, exercise, drugs may prevent diabetes in high-risk patients
Diet and exercise prevent diabetes
Diet high in vegetables, fruit and fiber/low in fat does not reduce risk of recurrent breast CA
Different SSRIs associated with specific birth defects; fluoxetine safest
Digital and local anesthesia equally effective for finger lacerations
Diphenhydramine ineffective in promoting sleep in infants (TIRED)
Discharge instructions for low-Na+ diet reduce HF readmissions
Discontinuing warfarin therapy indefinitely after GI bleeding assoc with worse outcomes
Distraction decreases child's anxiety during procedures
DMPA associated with reduced risk for ovarian cancer
Don't add aspirin to warfarin therapy except with mechanical heart valve
Door-to-balloon time important in STEMI
Dopamine worse for cardiogenic shock, associated with arrythmias
Dose-response relationship of alcohol in adverse pregnancy outcomes
Doula support decreases cesarean rate
Doxycycline prophylaxis effective for tick-borne relapsing fever
Dressing choice unimportant for leg ulcers
Dried plums = fiber for chronic constipation
Dronedarone prevents AF recurrence but effect on symptoms unknown
Dronedarone reduces hospitalization but not mortality in atrial fibrillation
Droperidol offers advantages for quelling violent behavior in the ED
Drotrecogin ineffective in septic children (RESOLVE)
3-drug approach more effective than nicotine replacement alone
Duct tape ineffective for common viral warts
Duct tape ineffective in warts in kids
Duloxetine decreases pain of diabetic neuropathy
Dutasteride slows progression in men with low-grade prostate cancer (REDEEM)
Dyspepsia: test-and-treat is best approach
Dyspeptic symptoms and endoscopic findings not closely associated
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Dabigatran associated with increased risk of coronary events