| Browse by Title Pacifier use associated with recurrent acute otitis media Pain severity does not predict outcomes with AMI Pain tx decreases agitation in nursing homes PA-led rapid response team beneficial Pancreatic cancer risk increased in families with Lynch syndrome Pantoprozole more effective than somatostatin for peptic ulcer rebleeding Parathyroid hormone prevents recurrent fractures Paroxetine blocks effect of tamoxifen on breast cancer Patent foramen ovale not necessarily associated with stroke recurrence Patients like access to their own records; their doctors don't mind Patient-specific fall prevention plan reduces fall rates in older hospitalized patients PCI not useful for occluded vessel after completed STEMI PCI provides short-term quality of life improvement in stable angina (COURAGE) PCI similar to CABG in nonprotected left main disease PCP diagnosis of depression: not very accurate Peanut and tree nut consumption during pregnancy may decrease risk of allergic disease in children PECARN and CHALICE best rules in children with head injuries Pedigree identifies hereditary breast cancer syndromes Pedometer-based programs result in modest weight loss Pedometer use increases physical activity and may promote weight loss Peer-based interventions to promote behavior change produce mixed results PEG helpful in childhood constipation, fecal impaction PEG more effective than tegaserod for chronic constipation PEG safe and effective for up to 6 months in chronic constipation Pelvic floor muscle training reduces urinary incontinence in pregnancy Pergolide, cabergoline increase risk of heart valve damage Periconception antibiotics associated with birth defects Perinatal mortality associated with macrosomia Perinatal steroids not associated with adverse CV function 7-10 years later Perindopril+indapamide improves outcomes in high-risk pts with DM (ADVANCE) Perioperative beta-blockers = placebo for noncardiac surgery Perioperative metoprolol: fewer CV events and MIs, more deaths and strokes (POISE) Perioperative statin use decreased post-op MI and AF in statin-naïve patients Peri-op fluvastatin reduces myocardial ischemia after vascular surgery Pessary reduces preterm birth among women with a short cervix identified mid-second trimester Pharmacist-assisted Web-based care improves hypertension control Phlebotomy decreased cancer risk in patients with PAD PHQ-15 reasonable for screening for somatoform disorders in primary care Physical activity and the risk of bleeding in children with hemophilia Physician-, biomarker-, and symptom-based adjustment of inhaled steroids all similar for adult asthma control Physicians should ask surrogate decision-makers about life-support preference Pimecrolimus (Elidel) cream minimally effective for perioral dermatitis Pimecrolimus ineffective for intertriginous psoriasis Pioglitazone does not increase cardiovascular events (PROactive) Pioglitazone prevents diabetes, but increases weight and risk of edema Placebo = antibiotics for skin abscesses in children Placebo almost as effective as hypnotics in adults Placebo or sham interventions strongly affect subjective outcome measures Platelet rich plasma ineffective in chronic Achilles tendinopathy Platelet-rich plasma injection does not improve chronic Achilles tendinopathy Pneumatic compression devices effective for RLS Pneumococcal conjugate vaccine prevents meningitis Pneumococcal polysaccharide vaccine of questionable benefit for adults Pneumonia: 3 days of antibiotics for uncomplicated course Pneumonia can be treated with 3 to 5 days of abx Point-of-care CRP testing slightly decreases abx for RTI Polypill improves CV risk markers, no data on outcomes (TIPS) Polyunsaturated fat diet not effective to prevent heart disease Poor agreement on interpretation of fetal heart rate tracings Poor evidence for antioxidants for arthritis Poor-quality evidence for steroid injection in pts with frozen shoulder Poor research quality for newborn hearing testing, screening, and treatment Postcoital bleeding of limited use in determining cervical cancer risk PPI helpful for HP-negative dyspepsia with normal endoscopy, especially if overweight PPI lansoprazole not effective for improving asthma control in children PPIs improve postnasal drip symptoms PPIs not helpful for GERD-related chronic laryngitis PPI use associated with increased risk of spontaneous bacterial peritonitis in cirrhotic adults PPI use linked with recurrent C difficile infection PPI use reduces benefit of clopidogrel post-MI Pragmatic primary care trial finds LTI similarly effective as inhaled steroid, LABA Praying for others doesn't prevent surgery complications (STEP) Prediction model can decrease prostate biopsies in men with abnormal PSA Prednisolone but not acyclovir effective for Bell's palsy Prednisolone effective short-term for complex regional pain syndrome Prednisone following bare metal stent implantation improves outcomes Pregabalin = placebo for painful HIV-associated neuropathy Pregnancy outcomes in women with systemic sclerosis worse than in general population Prenatal supplementation with DHA-rich fish oil does not improve outcomes Preop chlorhexidine-alcohol more effective than povidone-iodine in preventing surgical-site infections Pre-op smoking cessation decreases complication rate Prepregnancy or gestational diabetes increases risk of perinatal depression Prescription omega-3 fatty acids do not reduce risk of recurrent A fib Presence of risk factors doesn't predict acute coronary syndrome Presenting risks in different ways affects perceptions Preterm birth associated with prior abortion Preterm birth associated with reduced survival and reproduction Preterm birth increased after treatment for CIN Preterm births not reduced by periodontal treatment Pretreatment eradication of H. pylori improves NSAID safety Pretreatment with omeprazole before endoscopy reduces bleeding Preventing breast cancer effective in postmenopausal women Preventing falls in the hospital: not much data Preventing mastoiditis not a good antibiotic rationale Primary care physicians can help patients lose weight Proactive communication strategy reduces stress in families of dying patients Probiotic decreases colicky crying Probiotic decreases IBS symptoms Probiotic decreases side effects of H. pylori treatment Probiotic improves functional abdominal pain in children Probiotics decrease antibiotic-associated diarrhea in children Probiotics decrease antibiotic-associated diarrhea risk Probiotics effective in preventing acute diarrhea, but not traveler's diarrhea Probiotics effective to prevent recurrent BV Probiotics increase mortality in severe pancreatitis (PROPATRIA) Probiotics may improve irritable bowel syndrome Probiotics prevent C. diff-associated diarrhea in patients taking antibiotics Probiotics prevent cold symptoms in children Probiotics reduce risk of antibiotic-associated diarrhea in children and adults Probiotics safe, minimally effective in newborns Probiotics somewhat helpful for IBS Probiotic yogurt prevents antibiotic-associated diarrhea in hospitalized patients Problem-solving therapy effective for depression with executive dysfunction Procalcitonin-guided algorithms reduce antibiotic use without affecting mortality Procalcitonin levels reduce antibiotic use in ICU Procalcitonin may distinguish bacterial from viral meningitis in kids Procalcitonin test can reduce antibiotic use in COPD Procalcitonin testing decreases antibiotic use Procalcitonin useless in managing febrile children Progestational agents reduce preterm birth Progesterone ineffective to reduce preterm twin birth Progestogens prevent preterm birth among women with prior preterm birth Prognosis of acute and persistent low back pain Prognosis of bicuspid aortic valve depends on age, severity of valve dysfunction Prognosis of cutaneous signs of neurofibromatosis type 1 Prognosis poor for nursing home residents started on dialysis Prognosis poor in advanced dementia Progress of induced labor slower than spontaneous labor Prolonged thromboprophylaxis after hip-replacement surgery decreases VTE Prolonged tocolysis after 48 hrs with oral nifedipine does not reduce adverse perinatal outcomes Promoting breastfeeding duration and exclusivity does not prevent childhood obesity Prompt tympanostomy tube insertion doesn't improve 9 yr outcomes Prophylactic abx not necessary after UTI in children Prophylactic dialysis reduces long-term dialysis in pts with renal failure after coronary angiography Prophylactic indomethacin prevents post-ERCP pancreatitis in high-risk patients Prophylactic salpingo-oophorectomy reduces ovarian cancer risk Prophylaxis effective for HIV-discordant heterosexual couples Prophylaxis not effective for tension-type headache Prophylaxis with continuous IV haloperidol decreased post-op delirium in elderly Propranolol reduces severe infantile hemangiomas Proprioceptive training decreases recurrent ankle sprains Prostaglandin inhibitors best for tocolysis Prostate cancer screening: no mortality benefit after 13 years of follow-up (PLCO) Prostate cancer screening increases harm risk without decreasing mortality PSA screening does not decrease mortality PSA screening does not reduce mortality from prostate CA (PLCO) PSA screening for prostate cancer not recommended (USPSTF) PSA screening has marginal effect on mortality in European study (ERSPC) Psoriasis associated with increased risk of atrial fibrillation and stroke Psychiatric problems do not increase after induced abortion Psychological interventions reduce onset of depression Psychotherapy improves CV outcomes in at-risk patients (SUPRIM) PT combined with patient education reduces falls in older hospitalized patients Pulmonary Embolism (PE) Severity Index predicts low risk PE patients Pulse oximetry screening for congenital heart defects: modest sensitivity, high specificity, unknown outcomes Pulse oximetry to screen for congenital heart disease in newborns Pyloric stenosis has strong heritability risk
| |