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Infections in immunosuppressed and cancer patients

Causes of infection in patients with cancer

  • Neutropenia (after cytotoxic chemotherapy)
    • Gram-negative rod bacteria (enterobacteria, pseudomonas)
    • Staphylococcus aureus
    • Staphylococcus epidermidis (central venous catheter)
    • Viridans streptococci (mucositis)
    • Enterococci (perianal infections)
    • Yeasts (Candida species)
    • Aspergillus moulds (especially in severe and prolonged, i.e. lasting for several weeks, neutropenia)
  • Disorders of humoral immunity (myeloma, chronic lymphocytic leukaemia)
    • Bacteria with a capsule (pneumococci, Haemophilus influenzae, meningococcus)
  • Splenectomized patients
    • Pneumococci, Haemophilus influenzae, meningococcus
  • Disorders of cell-mediated immunity (HIV infection, lymphomas, organ transplantations)
    • Mycobacteria
    • Listeria
    • Salmonella
    • Herpes viruses (Herpes simplex, Varicella zoster, cytomegalovirus)
    • Toxoplasma
    • Pneumocystis jirovecii
    • Cryptococcus
    • Candida yeasts
    • Aspergillus moulds

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