MEDLINE Journals

    Sclerotherapy with use of doxycycline after percutaneous drainage of postoperative lymphoceles.

    Authors

    Caliendo MV, Lee DE, Queiroz R, et al. 

    Source

    J Vasc Interv Radiol 2001 Jan; 12(1) :73-7.

    Abstract

    PURPOSE
    To assess the use of doxycycline as a sclerosing agent after percutaneous drainage of postoperative lymphoceles.
    MATERIALS AND METHODS
    Symptomatic postoperative lymphoceles (n = 21) in 18 patients were treated by percutaneous tube drainage for an average of 10.8 days. Sclerosis was performed when the patient became asymptomatic, drainage had slowed to less than 30 mL/d and follow-up imaging (CT or US) showed either near complete or total resolution of the lymphocele. Doxycycline (500 mg) combined with 1% lidocaine (5 mL) was instilled into the cavity with use of a syringe after any remaining lymphocele fluid was removed through the tube. When possible, patients were instructed to perform a series of maneuvers for the next hour to distribute the sclerosing agent evenly throughout the cavity. After 1 hour, the sclerosing agent was aspirated from the cavity and the drainage tube was removed. Three patients with four lymphoceles underwent sclerotherapy immediately after percutaneous insertion of a drainage tube and aspiration of the lymphocele. No patients underwent previous sclerosis with any agent.
    RESULTS
    Successful treatment of postoperative lymphoceles was achieved in 17 of 18 patients. Primary success was achieved in 17 of 21 lymphoceles treated. There were four lymphocele recurrences in three patients. Three of the four recurrences were successfully treated by means of repeated drainage and sclerotherapy. One recurrent lymphocele persisted after re-treatment with 1 g of doxycycline. This patient underwent successful surgical repair. There were no complications related to doxycycline sclerosis. The mean duration of drainage for initial and recurrent lymphoceles was 10.8 days (range, 0-30 days).
    CONCLUSION
    Sclerotherapy with use of doxycycline after percutaneous drainage is an easy, safe, inexpensive, and effective means of treating postoperative lymphoceles.

    Mesh

    Aged
    Aged, 80 and over
    Anti-Bacterial Agents
    Doxycycline
    Drainage
    Female
    Humans
    Lymphocele
    Male
    Middle Aged
    Postoperative Complications
    Sclerosing Solutions
    Sclerotherapy

    Language

    eng

    Pub Type(s)

    Journal Article

    PubMed ID

    11200357

    Content Manager
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