MEDLINE Journals

    Increased brain activity in frontal and parietal cortex underlies the development of visuospatial working memory capacity during childhood.

    Authors

    Klingberg T, Forssberg H, Westerberg H 

    Institution

    Department of Neuropediatrics, Astrid Lindgrens Children's Hospital, Karolinska Institute, Stockholm, Sweden. torkel.klingberg@neuro.ki.se

    Source

    J Cogn Neurosci 2002 Jan 1; 14(1) :1-10.

    Abstract

    The aim of this study was to identify changes in brain activity associated with the increase in working memory (WM) capacity that occurs during childhood and early adulthood. Functional MRI (fMRI) was used to measure brain activity in subjects between 9 and 18 years of age while they performed a visuospatial WM task and a baseline task. During performance of the WM task, the older children showed higher activation of cortex in the superior frontal and intraparietal cortex than the younger children did. A second analysis found that WM capacity was significantly correlated with brain activity in the same regions. These frontal and parietal areas are known to be involved in the control of attention and spatial WM. The development of the functionality in these areas may play an important role in cognitive development during childhood.

    Mesh

    Adolescent
    Attention
    Child
    Cognition
    Female
    Frontal Lobe
    Humans
    Magnetic Resonance Imaging
    Male
    Memory, Short-Term
    Parietal Lobe
    Space Perception

    Language

    eng

    Pub Type(s)

    Journal Article

    PubMed ID

    11798382

    Content Manager
    Related Content

    Development of a superior frontal-intraparietal network for visuo-spatial working memory.

    Cortical capacity constraints for visual working memory: dissociation of fMRI load effects in a fronto-parietal network.

    Stronger synaptic connectivity as a mechanism behind development of working memory-related brain activity during childhood.

    Evidence for quantitative domain dominance for verbal and spatial working memory in frontal and parietal cortex.

    Functional neuroanatomy of visuo-spatial working memory in Turner syndrome.

    Visuospatial executive function in Turner syndrome: functional MRI and neurocognitive findings.

    Transcranial magnetic stimulation of the parietal cortex facilitates spatial working memory: near-infrared spectroscopy study.

    Neural systems for visual orienting and their relationships to spatial working memory.