Brompheniramine With Phenylephrine

General

Dimetapp Children's Cold and Allergy, and many others
Antihistamine + decongestant

No	No	3	C

Key

Elixir (Dimetapp Children's Cold and Allergy) [OTC]: Brompheniramine 1 mg + phenylephrine 2.5 mg/5 mL (237 mL)

Chewable tab (Dimetapp Children's Cold and Allergy) [OTC]: Brompheniramine 1 mg + phenylephrine 2.5 mg

Dosing

All doses based on brompheniramine component.
2–<6 yr: 1 mg Q4 hr PO up to a max. dose of 6 mg/24 hr
6–12 yr: 2 mg Q4 hr PO up to a max. dose of 12 mg/24 hr
≥12 yr: 4 mg Q4 hr PO up to a max. dose of 24 mg/24 hr

Alternatively, dosing based on specific dosage forms/products. CAUTION: These products are available in different concentrations.
Oral, elixir (Dimetapp Children's Cold and Allergy):
6–<12 yr: 10 mL Q4 hr PO up to a max. dose of 60 mL/24 hr
≥12 yr: 20 mL Q4 hr PO up to a max. dose of 120 mL/24 hr
Oral, chewable tab (Dimetapp Children's Cold and Allergy):
6–<12 yr: Chew 2 tablets Q4 hr PO; max. dose: 6 doses/24 hr
≥12 yr: Chew 4 tablets Q4 hr PO; max. dose: 6 doses/24 hr

Notes

Generally not recommended for treating URIs for infants. No proven benefit for infants and young children with URIs. Over the counter (OTC or non-prescription) use of this product is not recommended for children younger than 6 yr due to reports of serious adverse effects (cardiac and respiratory distress, convulsions, and hallucinations) and fatalities (from unintentional overdosages, including combined use of other OTC products containing the same active ingredients).

Contraindicated with use of MAO inhibitors; concurrent use and within 14 days after discontinuing MAO inhibitor. Use with caution in narrow-angle glaucoma, bladder neck obstruction, asthma, pyloroduodenal obstruction, symptomatic prostatic hypertrophy, hypertension, coronary artery disease, diabetes mellitus, and thyroid disease. Discontinue use 48 hours prior to allergy skin testing. May cause drowsiness, fatigue, CNS excitation, xerostomia, blurred vision, and wheezing.