Physiological rationale for suppression of fever.
Two critical assumptions are made when prescribing antipyretic therapy. One is that fever is, at least in part, noxious, and the other is that suppression of fever will reduce, if not eliminate, the noxious effects of fever. At present, neither assumption has been validated experimentally.
Medical Care Clinical Center, Veterans Affairs Maryland Health Care System, and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Philip.Mackowiak@med.va.gov
SourceClinical infectious diseases : an official publication of the Infectious Diseases Society of America 31 Suppl 5: 2000 Oct pg S185-9
Clinical Trials as Topic
Reproducibility of Results
Pub Type(s)Journal Article