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A large-scale validation study of the Medication Adherence Rating Scale (MARS).

Abstract

Adherence to medication is an important predictor of illness course and outcome in psychosis. The Medication Adherence Rating Scale (MARS) is a ten-item self-report measure of medication adherence in psychosis [Thompson, K., Kulkarni, J., Sergejew, A.A., 2000. Reliability and validity of a new Medication Adherence Rating Scale (MARS) for the psychoses. Schizophrenia Research. 42. 241-247]. Although initial results suggested that the scale has good reliability and validity, the development sample was small. The current study aimed to establish the psychometric properties of the MARS in a sample over four times larger. The scale was administered to 277 individuals with psychosis, along with measures of insight and psychopathology. Medication adherence was independently rated by each individual's keyworker. Results showed the internal consistency of the MARS to be lower than in the original sample, though adequate. MARS total score correlated weakly with keyworker-rated adherence, hence concurrent validity of the scale appeared only moderate to weak. The three factor structure of the MARS was replicated. Examination of the factor scores suggested that the factor 1 total score, which corresponds to the Medication Adherence Questionnaire [Morisky,D.E., Green,L.W. and Levine,D.M., 1986. Concurrent and predictive validity of a self-reported measure of medication adherence. Medical Care. 24, 67-74] may be a preferable measure of medication adherence behaviour to the total scale score.

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  • Publisher Full Text
  • Authors

    Fialko L, Garety PA, Kuipers E, Dunn G, Bebbington PE, Fowler D, Freeman D

    Source

    Schizophrenia research 100:1-3 2008 Mar pg 53-9

    MeSH

    Adult
    Antipsychotic Agents
    Attitude to Health
    Factor Analysis, Statistical
    Female
    Humans
    Male
    Patient Compliance
    Personality Inventory
    Psychiatric Status Rating Scales
    Psychometrics
    Psychotic Disorders
    Questionnaires
    Recurrence
    Reproducibility of Results
    Schizophrenia
    Schizophrenia, Paranoid
    Schizophrenic Psychology

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    18083007