Abstract

Diltiazem hydrochloride is a commonly prescribed medication in the treatment of cardiovascular disease. A case of diltiazem-induced hyperpigmentation in a patient after significant sun exposure is reported. The morphological appearance was reticulated and slate-gray to blue in color. The pathogenesis of the hyperpigmentation is discussed and possible treatment options are reviewed.

Authors

Hanson M, Petronic-Rosic V

Institution

Section of Dermatology, Department of Medicine, University of Chicago, Chicago, IL, USA.

Source

Journal of drugs in dermatology : JDD 7:8 2008 Aug pg 792-3

MeSH

Administration, Topical
Anti-Inflammatory Agents
Calcium Channel Blockers
Coronary Vasospasm
Dermatitis, Phototoxic
Diltiazem
Drug Eruptions
Fluocinonide
Humans
Hyperpigmentation
Keratinocytes
Male
Middle Aged
Necrosis
Skin

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

18720699