Abstract

OBJECTIVE
The purpose of this study was to compare rectal misoprostol (RM) with 15-methyl prostaglandin F2alpha (PGF(2alpha)) for the management of retained placenta after second-trimester deliveries.
STUDY DESIGN
A retrospective study of all second-trimester deliveries between the years 2000 and 2005 was performed. Women were divided into 2 groups, depending on whether they received RM or PGF(2alpha) after the delivery.
RESULTS
Three hundred three second-trimester deliveries were analyzed. The time from the administration of medications to the placental delivery was significantly shorter in women who received PGF(2alpha), compared with the RM group (49.5 vs 89 minutes; P < .01). Women who received PGF(2alpha) had lower rates of retained placenta (4.9% vs 12.4%; P = .02).
CONCLUSION
The use of PGF(2alpha) after second-trimester deliveries results in shorter third stage of labor and lower rates of retained placenta compared with RM.

Links

Publisher Full Text

Authors

Sundaram S, Diaz JP, González-Quintero VH, Verma U

Institution

Department of Obstetrics and Gynecology, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.

Source

American journal of obstetrics and gynecology 200:5 2009 May pg e24-6

MeSH

Abortifacient Agents, Nonsteroidal
Abortion, Therapeutic
Administration, Rectal
Adult
Carboprost
Female
Humans
Misoprostol
Placenta, Retained
Pregnancy
Pregnancy Trimester, Second
Retrospective Studies
Treatment Outcome
Young Adult

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

19136084