Unbound MEDLINE

Adherence to antiretroviral therapy: a survey of factors associated with medication usage.

Abstract

The use of highly active antiretroviral therapy (HAART) has decreased morbidity and mortality for people living with HIV/AIDS, but adherence to HAART is a critical factor in successful treatment. Adherence to medication is a complex and poorly understood behavior. A survey was undertaken to evaluate subjective correlates of adherence and non-adherence based on previously distilled themes from a qualitative study of adherence. A 60-question survey was completed by patients in the outpatient clinic setting regarding demographics, CD4 cell count, viral load, adherence, and screening questions about medication usage and attitudes toward HIV. Ninety-eight adherent and 34 non-adherent patients completed the survey. After logistic regression analysis, several questions appeared to be the main predictors of non-adherence: Have you ever thought of having HIV as a "punishment?" Do you feel that your medicines are hard to take? Do you believe the medicines for HIV that you take are working for you? These questions may be helpful in the development of a clinically useful screening tool to assess patients at risk for non-adherence.

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  • Publisher Full Text
  • Authors

    Duggan JM, Locher A, Fink B, Okonta C, Chakraborty J

    Institution

    Department of Medicine, Ryan White Program at the University of Toledo, Toledo, OH, USA. joan.duggan@utoledo.edu

    Source

    AIDS care 21:9 2009 Sep pg 1141-7

    MeSH

    Adolescent
    Adult
    Aged
    Anti-Retroviral Agents
    Antiretroviral Therapy, Highly Active
    Attitude to Health
    Female
    HIV Infections
    Humans
    Male
    Medication Adherence
    Middle Aged
    Motivation
    Questionnaires
    Regression Analysis
    Socioeconomic Factors
    Young Adult

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    20024773