Abstract

Systemic lupus erythematosus (SLE) is not an uncommon condition. Most neurologists are well aware that it can cause a wide range of neurological complications, and SLE almost invariably appears on 'differential diagnosis' lists in cases of clinical uncertainty. However, the precise nature of the manifestations of SLE in the central and peripheral nervous systems is perhaps less widely understood, and misperceptions about phenomenology and treatment are common. Here we survey some of the main primary neurological complications of SLE--'neurolupus'--while acknowledging that secondary problems, either iatrogenic or relating to other consequences of SLE (eg, hypertensive CNS disease, for example, secondary to renal lupus) are neither less serious nor less treatable.

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Publisher Full Text

Authors

Joseph FG, Scolding NJ

Institution

Consultant Neurologist, Neville Hall Hospital, Abergavenny and the Royal Gwent Hospital, Newport, UK.

Source

Practical neurology 10:1 2010 Feb pg 4-15

MeSH

Diagnosis, Differential
Humans
Lupus Erythematosus, Systemic
Nervous System Diseases
Severity of Illness Index

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

20130291