Unbound MEDLINE

Reactions to Aquaphor: is bisabolol the culprit?

Abstract

Bisabolol is a sesquiterpene alcohol compound derived from the German chamomile plant, a member of the Compositae family. Only two case reports of adults with allergic contact dermatitis to this chemical exist in the literature, and we describe three more cases of children with recalcitrant atopic dermatitis found to have potential allergic contact dermatitis to bisabolol- a component of the Aquaphor emollient they were using to treat their atopic dermatitis. Of note, Compositae dermatitis has been shown to have a higher prevalence in children with atopic dermatitis, so it is important for physicians to be aware of the potential allergens (like bisabolol) in products they are recommending as first line treatments.

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  • Publisher Full Text
  • Authors

    Jacob SE, Hsu JW

    Institution

    University of California, San Diego-Rady Children's Hospital, California 92123, USA. sjacob@contactderm.net

    Source

    Pediatric dermatology 27:1 pg 103-4

    MeSH

    Chamomile
    Child
    Child, Preschool
    Dermatitis, Allergic Contact
    Dermatitis, Atopic
    Female
    Humans
    Male
    Plant Extracts
    Sesquiterpenes

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    20199429