Abstract

This study investigated the antibacterial effect of a resin composite matrix with or without incorporated triclosan (0.3 wt%) on Streptococcus mutans, Actinomyces viscosus and Lactobacillus casei. In the quantitative assay, bacterial suspensions were filled into 20-μl cavities within temporary restorative resins. After 0, 4, 8, 12, 24 and 48 h of incubation, the suspensions were removed from the restoratives and the numbers of viable bacteria were determined. Bacterial suspensions incubated without restoratives served as the controls. Ten replicates were carried out for each experiment. The resin composite containing triclosan demonstrated variable degrees of antibacterial activity against the microorganisms, revealing a significant inhibitory effect on S. mutans within 12 h compared to the control. The viable counts of A. viscosus significantly decreased after 24 h. A significant reduction of L. casei was observed after 48 h. The unloaded resin composite did not reveal a marked antibacterial effect. The resin composite loaded with triclosan might be beneficial in preventing cavity contamination and minimizing the risk of pulpal irritation in the short-term.

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Publisher Full Text

Authors

Rathke A, Staude R, Muche R, Haller B

Institution

Department of Operative Dentistry and Periodontology, University of Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany. andreas.rathke@uniklinik-ulm.de

Source

Journal of materials science. Materials in medicine 21:11 2010 Nov pg 2971-7

MeSH

Actinomyces viscosus
Anti-Bacterial Agents
Colony Count, Microbial
Composite Resins
Drug Carriers
Humans
Lactobacillus casei
Materials Testing
Microbial Sensitivity Tests
Microbial Viability
Models, Biological
Mouth
Resins, Synthetic
Streptococcus mutans
Triclosan

Pub Type(s)

Evaluation Studies
Journal Article

Language

eng

PubMed ID

20640491