Abstract

The outcome of childhood acute lymphoblastic leukemia in India has been inferior to more than 80% cure rates in developed nations. This study was done to analyze the outcome of acute lymphoblastic leukemia in India over 4 decades. There has been a gradual improvement in survival rates of up to >70% in some centers along with a decline in relapse and mortality. However, these results cannot be generalized to the entire nation. There is a crying need to address treatment abandonment, take quality improvement, educational and financial initiatives; cooperative research into risk factors and disease biology, and the implementation of risk stratification along with the assessment of response to therapy.

Links

Publisher Full Text

Authors

Kulkarni KP, Arora RS, Marwaha RK

Institution

Division of Pediatric Hematology Oncology, Stollery Children Hospital, University of Alberta, Canada.

Source

Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 33:6 2011 Aug pg 475-9

MeSH

Child
Developing Countries
Humans
India
Poverty
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Prognosis
Review Literature as Topic
Survival Rate
Time Factors

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21792045