Abstract

Epidermolytic hyperkeratosis is a form of ichthyosis normally resistant to topical treatments. Female patient monitored since 1978 diagnosed with epidermolytic hyperkeratosis. Clinical examination showed generalized hyperkeratosis and scaling. Given that no other treatments were available at the time, the patient was initially treated with keratolytic, systemic vitamin A and moisturizers, with no improvement. In 1986, with the development of oral retinoids, etretinate was introduced. In 1998 this was replaced by acitretin. The patient is receiving 25 mg/day after 23 years of using oral retinoids. Significant improvement of the condition and patient's quality of life has been noted.

Links

Publisher Full Text

Authors

Nassif PW, Nakandakari S, Fogagnolo L, Contin LA, Alves CJ

Institution

Uninga Faculty, Maringa, Parana, Brazil. priwolf@gmail.com

Source

Anais brasileiros de dermatologia 86:4 Suppl 1 pg S72-5

MeSH

Acitretin
Female
Humans
Hyperkeratosis, Epidermolytic
Middle Aged
Retinoids
Time Factors

Pub Type(s)

Case Reports
Journal Article

Language

eng por

PubMed ID

22068776