Abstract

Hyperthrofic lichen planus is considered a variant of lichen planus with marked epidermal hyperplasia in response to persistent itch. It is clinically, characterized by symmetric hyperkeratotic plaques, of purplish-grey color, often located in the pretibial region. Intense pruritus, refractoriness to conventional treatments and the possibility of association of the long-term injuries with squamous cell carcinoma requires an effective treatment. The first-line treatment is corticosteroids which can be applied either topically or systemically. Other therapeutic modalities proposed are: NB-UVB phototherapy or PUVA, immunosuppressive drugs and systemic retinoids, notably acitretin. We report a case with exuberant clinical presentation of hyperthrofic lichen planus with excellent response to acitretin after nine months of treatment.

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Publisher Full Text

Authors

Jaime TJ, Jaime TJ, Guaraldi Bde M, Melo DF, Jeunon T, Lerer C

Institution

Hospital Naval Marcílio Dias, Rio de Janeiro, Brasil. thaisjerez@yahoo.com.br

Source

Anais brasileiros de dermatologia 86:4 Suppl 1 pg S96-9

MeSH

Acitretin
Female
Hand Dermatoses
Humans
Keratolytic Agents
Lichen Planus
Middle Aged

Pub Type(s)

Case Reports
Journal Article

Language

eng por

PubMed ID

22068783