Nutrition strategies to improve physical capabilities in Duchenne muscular dystrophy.
There is no current cure for Duchenne muscular dystrophy (DMD), and palliative and prophylactic interventions to improve the quality of life of patients remain limited, with the exception of corticosteroids. This article describes 2 potential nutritional interventions for the treatment of DMD, green tea extract (GTE) and the branched-chain amino acid leucine, and their positive effects on physical activity. Both GTE and leucine are suitable for human consumption, are easily tolerated with no side effects, and, with appropriate preclinical data, could be brought forward to clinical trials rapidly.
Department of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg, VA 24061, USA.
SourcePhysical medicine and rehabilitation clinics of North America 23:1 2012 Feb pg 187-99, xii-xiii
Muscular Dystrophy, Duchenne
TOR Serine-Threonine Kinases
Pub Type(s)Journal Article