Unbound MEDLINE

Nutrition strategies to improve physical capabilities in Duchenne muscular dystrophy.

Abstract

There is no current cure for Duchenne muscular dystrophy (DMD), and palliative and prophylactic interventions to improve the quality of life of patients remain limited, with the exception of corticosteroids. This article describes 2 potential nutritional interventions for the treatment of DMD, green tea extract (GTE) and the branched-chain amino acid leucine, and their positive effects on physical activity. Both GTE and leucine are suitable for human consumption, are easily tolerated with no side effects, and, with appropriate preclinical data, could be brought forward to clinical trials rapidly.

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  • Authors

    Davoodi J, Markert CD, Voelker KA, Hutson SM, Grange RW

    Source

    Physical medicine and rehabilitation clinics of North America 23:1 2012 Feb pg 187-99, xii-xiii

    MeSH

    Animals
    Camellia sinensis
    Dietary Supplements
    Humans
    Leucine
    Motor Activity
    Muscular Dystrophy, Duchenne
    Phytotherapy
    Plant Extracts
    Signal Transduction
    TOR Serine-Threonine Kinases

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    22239883