Unbound MEDLINE

Effect of dietary copper source on response to coliform mastitis in dairy cows.

Abstract

The effect of organic or inorganic dietary Cu on Escherichia coli mastitis was investigated in first-lactation heifers. Twenty-eight primigravid Holstein heifers were assigned to 3 treatments in a completely randomized block design with 10 blocks of 3 animals grouped by expected calving date. Treatments were as follows: basal diet [7.1 mg Cu/kg of dry matter (DM); CON] and diets supplemented with Cu (10 mg/kg of DM) as Cu sulfate (CUS) or as Cu proteinate (CUP). Treatments were fed individually from 60 d prepartum through 49 d of lactation. All heifers were marginally deficient at the onset of the experiment (liver Cu of 60 mg/kg) and did not differ between groups. Mean liver Cu concentrations were about 3-fold greater in CUS and CUP compared with CON at d 0, 21, and 42 of lactation. At d 34 postpartum, one pathogen-free quarter per cow was infused with Escherichia coli strain 727. Copper supplementation did not lower peak responses to challenge; however, CUP tended to offer some benefits: milk bacterial count with CUP was lower compared with CON at 24, 48, and 72 h and lower than CUS at 24 and 96 h, and postchallenge milk production tended to be greater for CUP. Clinical udder score was lower at 12 h for CUP and CUS compared with CON, and at 144 h CUP had lower clinical scores compared with CUS or CON. Somatic cell count, dry matter intake, plasma Cu, and plasma ceruloplasmin did not differ between treatments. Compared with the control diet or Cu sulfate supplement, supplementation with Cu proteinate tended to improve the clinical status of cows after live E. coli intramammary challenge.

Links

  • Publisher Full Text
  • Authors

    Scaletti RW, Harmon RJ

    Institution

    Alltech Center for Animal Nutrigenomics and Applied Animal Nutrition, Alltech Inc., Nicholasville, KY 40356-9765, USA. rscaletti@alltech.com

    Source

    Journal of dairy science 95:2 2012 Feb pg 654-62

    MeSH

    Animal Feed
    Animals
    Cattle
    Copper
    Diet
    Dietary Supplements
    Escherichia coli
    Escherichia coli Infections
    Female
    Lactation
    Liver
    Mastitis, Bovine
    Milk

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    22281330