Abstract

A 44-year-old woman was diagnosed with Graves' disease in 1995 and over the following 12 months developed thyroid dermopathy (pretibial myxoedema). Despite being trialled on multiple recognized therapies over the course of 11 years, the patient's dermopathy progressively worsened. She developed ocular proptosis, elephantiasic thyroid dermopathy and acropachy in both hands. In mid 2006, the patient was started on rituximab and plasmapheresis, with rapid response. The patient's condition stabilized and in October 2009 at the age of 58 years she was able to cease therapy.

Links

Publisher Full Text

Authors

Heyes C, Nolan R, Leahy M, Gebauer K

Institution

Department of Dermatology, Fremantle Hospital, Western Australia, Australia. chrisheyes@gmail.com

Source

The Australasian journal of dermatology 53:1 2012 Feb pg e1-4

MeSH

Adult
Antibodies, Monoclonal, Murine-Derived
Combined Modality Therapy
Female
Graves Disease
Hand Dermatoses
Humans
Immunologic Factors
Leg Dermatoses
Myxedema
Plasmapheresis
Treatment Outcome

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22309343