Abstract

OBJECTIVE
To examine the early results of the David V valve-sparing aortic root replacement procedure in expanded, higher risk clinical scenarios with appropriately selected patients.
METHODS
From 2005 to 2011, 150 David V valve-sparing aortic root replacements were performed within Emory Healthcare. A total of 78 patients (expanded group) had undergone the David V in expanded, difficult clinical settings such as emergent type A dissection (n = 29), grade 3+ or greater aortic insufficiency (AI) (n = 53), or reoperative cardiac surgery (n = 14). These patients were evaluated and compared with a group of 72 patients (traditional group) with less than grade 3+ AI who underwent a David V in a traditional, elective setting. The mean follow-up was 19 months (range, 1-72), and the follow-up data were 88% complete.
RESULTS
There were 3 operative deaths (2.2%), all occurring in the expanded group. The overall patient survival at 6 years was 95%. Three patients required aortic valve replacement: two for severe AI and one for fungal endocarditis. Both groups had concomitant cusp repairs performed in conjunction with the David V (traditional, n = 10; and expanded, n = 16; P = .27). At follow-up, freedom from moderate AI was 93%, and the freedom from aortic valve replacement was 98%. No significant difference was observed in the freedom from moderate AI between the expanded and traditional groups (91% vs 95%, respectively; P = .16).
CONCLUSIONS
In selected patients possessing appropriate aortic cusp anatomy, the David V can be safely and effectively performed for the expanded indications of aortic dissection, severe AI, and reoperative cardiac surgery with low operative risk. Valve function has remained excellent in the short term, providing evidence of durability and a low rate of valve-related complications.

Links

Publisher Full Text

Publisher Full Text

Authors

Leshnower BG, Guyton RA, Myung RJ, Puskas JD, Kilgo PD, McPherson L, Chen EP

Institution

Clinical Research Unit, Division of Cardiothoracic Surgery, Joseph B Whitehead Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA.

Source

The Journal of thoracic and cardiovascular surgery 143:4 2012 Apr pg 879-84

MeSH

Adult
Aortic Diseases
Aortic Valve
Blood Vessel Prosthesis
Blood Vessel Prosthesis Implantation
Cardiac Surgical Procedures
Chi-Square Distribution
Female
Georgia
Heart Valve Prosthesis Implantation
Hospital Mortality
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Patient Selection
Reoperation
Replantation
Retrospective Studies
Risk Assessment
Risk Factors
Time Factors
Treatment Outcome

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22329981