Case report: atypical lipomatous tumor with unusual extensive metaplastic ossification.
The presence of metaplastic ossification within atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) is a rare occurrence. When present, bone formation is most often found in association with a dedifferentiated component arising within the primary tumor. It is important for the radiologist not only to recognize the differential diagnosis of a calcified or ossified soft tissue mass but also be aware of the various soft tissue neoplasms, both aggressive and non-aggressive, that may show such features. We report a case of ALT/WDLPS with unusual extensive metaplastic bone formation without an element of dedifferentiated liposarcoma.
aDepartment of Radiology, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02215, USA.
SourceCancer imaging : the official publication of the International Cancer Imaging Society 12:1 2012 pg 25-30
Cyclin-Dependent Kinase 4
Magnetic Resonance Imaging
Proto-Oncogene Proteins c-mdm2
Soft Tissue Neoplasms
Technetium Tc 99m Medronate
Tomography, X-Ray Computed
Tumor Markers, Biological
Pub Type(s)Case Reports