Abstract

The presence of metaplastic ossification within atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) is a rare occurrence. When present, bone formation is most often found in association with a dedifferentiated component arising within the primary tumor. It is important for the radiologist not only to recognize the differential diagnosis of a calcified or ossified soft tissue mass but also be aware of the various soft tissue neoplasms, both aggressive and non-aggressive, that may show such features. We report a case of ALT/WDLPS with unusual extensive metaplastic bone formation without an element of dedifferentiated liposarcoma.

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Authors

Javery O, Jagannathan JP, Saboo SS, O'Regan K, Hornick JL, Ramaiya N

Institution

aDepartment of Radiology, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02215, USA.

Source

Cancer imaging : the official publication of the International Cancer Imaging Society 12:1 2012 pg 25-30

MeSH

Aged
Biopsy, Needle
Cyclin-Dependent Kinase 4
Diagnosis, Differential
Humans
Liposarcoma
Magnetic Resonance Imaging
Male
Metaplasia
Ossification, Heterotopic
Positron-Emission Tomography
Proto-Oncogene Proteins c-mdm2
Radiography, Interventional
Radiopharmaceuticals
Shoulder
Soft Tissue Neoplasms
Technetium Tc 99m Medronate
Tomography, X-Ray Computed
Tumor Markers, Biological

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22375305