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Case report: atypical lipomatous tumor with unusual extensive metaplastic ossification.

Abstract

The presence of metaplastic ossification within atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) is a rare occurrence. When present, bone formation is most often found in association with a dedifferentiated component arising within the primary tumor. It is important for the radiologist not only to recognize the differential diagnosis of a calcified or ossified soft tissue mass but also be aware of the various soft tissue neoplasms, both aggressive and non-aggressive, that may show such features. We report a case of ALT/WDLPS with unusual extensive metaplastic bone formation without an element of dedifferentiated liposarcoma.

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  • Authors

    Javery O, Jagannathan JP, Saboo SS, O'Regan K, Hornick JL, Ramaiya N

    Institution

    aDepartment of Radiology, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02215, USA.

    Source

    Cancer imaging : the official publication of the International Cancer Imaging Society 12:1 2012 pg 25-30

    MeSH

    Aged
    Biopsy, Needle
    Cyclin-Dependent Kinase 4
    Diagnosis, Differential
    Humans
    Liposarcoma
    Magnetic Resonance Imaging
    Male
    Metaplasia
    Ossification, Heterotopic
    Positron-Emission Tomography
    Proto-Oncogene Proteins c-mdm2
    Radiography, Interventional
    Radiopharmaceuticals
    Shoulder
    Soft Tissue Neoplasms
    Technetium Tc 99m Medronate
    Tomography, X-Ray Computed
    Tumor Markers, Biological

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    22375305