Unbound MEDLINE

Ultrasensitive electrochemical detection of prostate-specific antigen (PSA) using gold-coated magnetic nanoparticles as 'dispersible electrodes'.

Abstract

Herein, we demonstrate the use of modified gold-coated magnetic nanoparticles as 'dispersible electrodes' which act as selective capture vehicles for electrochemical detection of prostate-specific antigen (PSA). A key advantage of this system is the ability to quantify non-electrochemical active analytes such as proteins with unprecedented detection limits and fast response times.

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  • Publisher Full Text
  • Authors

    Chuah K, Lai LM, Goon IY, Parker SG, Amal R, Justin Gooding J

    Source

    Chemical communications (Cambridge, England) 48:29 2012 Apr 11 pg 3503-5

    MeSH

    Antibodies, Monoclonal
    Biosensing Techniques
    Electrochemistry
    Ferrosoferric Oxide
    Gold
    Microscopy, Electron, Scanning
    Microscopy, Electron, Transmission
    Nanoparticles
    Prostate-Specific Antigen

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    22389188