Abstract

This study compared 4 local anesthetics, 1% lidocaine, 1% lidocaine with sodium bicarbonate, 2% chloroprocaine, and 0.5% bupivacaine, in a double-blinded manner for pain on intradermal injection and pain during subsequent intravenous (IV) cannulation with an 18-gauge catheter. The subjects rated their pain, using 100-mm visual analog scales, related to the local injection itself and again after the IV catheter was inserted. No statistical differences were noted in pain scores after the injection of the local anesthetic (P = . 134) or on insertion of the IV catheter itself (P = .394). However, there was a low correlation between the pain perceived during the injection of local anesthetic and insertion of the IV catheter (r = 0.483; P = .001). We found that there were no differences in pain produced by 1% lidocaine, 1% lidocaine with sodium bicarbonate, 2% chloroprocaine, and 0.5% bupivacaine during intradermal injection. There were also no differences in pain produced by an 18-gauge IV catheter being inserted after administration of any of these local anesthetics. Thus, any of these 4 local anesthetics may be used, and the choice may be based on other factors such as price and convenience.

Links

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Authors

Beck RM, Zbierajewski FJ, Barber MK, Engoren M, Thomas R

Institution

Wayne State University, USA. ryanbeck30@gmail.com

Source

AANA journal 79:4 Suppl 2011 Aug pg S58-61

MeSH

Adult
Anesthetics, Local
Buffers
Bupivacaine
Catheterization, Peripheral
Double-Blind Method
Female
Humans
Injections, Subcutaneous
Lidocaine
Male
Middle Aged
Ohio
Pain
Procaine
Sodium Bicarbonate

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

22403968