American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer.


An update to the American Cancer Society (ACS) guideline regarding screening for the early detection of cervical precancerous lesions and cancer is presented. The guidelines are based on a systematic evidence review, contributions from 6 working groups, and a recent symposium cosponsored by the ACS, the American Society for Colposcopy and Cervical Pathology, and the American Society for Clinical Pathology, which was attended by 25 organizations. The new screening recommendations address age-appropriate screening strategies, including the use of cytology and high-risk human papillomavirus (HPV) testing, follow-up (eg, the management of screen positives and screening intervals for screen negatives) of women after screening, the age at which to exit screening, future considerations regarding HPV testing alone as a primary screening approach, and screening strategies for women vaccinated against HPV16 and HPV18 infections.


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  • Authors

    Saslow D

    Solomon D

    Lawson HW

    Killackey M

    Kulasingam SL

    Cain J

    Garcia FA

    Moriarty AT

    Waxman AG

    Wilbur DC

    Wentzensen N

    Downs LS

    Spitzer M

    Moscicki AB

    Franco EL

    Stoler MH

    Schiffman M

    Castle PE

    Myers ER

    American Cancer Society

    American Society for Colposcopy and Cervical Pathology

    American Society for Clinical Pathology


    American journal of clinical pathology 137:4 2012 Apr pg 516-42


    Cervical Intraepithelial Neoplasia
    Early Detection of Cancer
    Mass Screening
    Papillomavirus Infections
    Uterine Cervical Neoplasms
    Vaginal Smears

    Pub Type(s)

    Journal Article
    Practice Guideline
    Research Support, Non-U.S. Gov't



    PubMed ID