Abstract

The objective of this study was to investigate the effect of ochratoxin A (OTA) on serum biochemical parameters of pigs during subchronic treatment with 300 μg OTA/kg of feed for 30 days. OTA treatment resulted in significantly higher (p < 0.05) serum levels of creatinine, urea, potassium and alkaline phosphatase, and significantly lower levels of glucose and total protein. These changes in serum biochemical parameters in treated pigs were indicative of impaired liver and kidney function caused by OTA exposure.

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Publisher Full Text

Authors

Pleadin J, Perši N, Mitak M, Terzić S, Milić D, Vulić A, Brstilo M

Institution

Department of Veterinary Public Health, Croatian Veterinary Institute, Savska 143, 10000, Zagreb, Croatia. pleadin@veinst.hr

Source

Bulletin of environmental contamination and toxicology 88:6 2012 Jun pg 1043-7

MeSH

Alanine Transaminase
Alkaline Phosphatase
Animals
Bilirubin
Blood Glucose
Carcinogens
Creatinine
Male
Ochratoxins
Serum Albumin
Serum Globulins
Swine
Urea
alpha-Amylases

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22467008