Abstract

As the mean age of the global population increases, breast cancer in older individuals will be increasingly encountered in clinical practice. Management decisions should not be based on age alone. Establishing recommendations for management of older individuals with breast cancer is challenging because of very limited level 1 evidence in this heterogeneous population. In 2007, the International Society of Geriatric Oncology (SIOG) created a task force to provide evidence-based recommendations for the management of breast cancer in elderly individuals. In 2010, a multidisciplinary SIOG and European Society of Breast Cancer Specialists (EUSOMA) task force gathered to expand and update the 2007 recommendations. The recommendations were expanded to include geriatric assessment, competing causes of mortality, ductal carcinoma in situ, drug safety and compliance, patient preferences, barriers to treatment, and male breast cancer. Recommendations were updated for screening, primary endocrine therapy, surgery, radiotherapy, neoadjuvant and adjuvant systemic therapy, and metastatic breast cancer.

Links

Publisher Full Text

Authors

Biganzoli L, Wildiers H, Oakman C, Marotti L, Loibl S, Kunkler I, Reed M, Ciatto S, Voogd AC, Brain E, Cutuli B, Terret C, Gosney M, Aapro M, Audisio R

Institution

Sandro Pitigliani Medical Oncology Unit, Istituto Toscano Tumori, Hospital of Prato, Prato, Italy. lbiganzoli@usl4.toscana.it

Source

The lancet oncology 13:4 2012 Apr pg e148-60

MeSH

Aged
Breast Neoplasms
Breast Neoplasms, Male
Carcinoma, Intraductal, Noninfiltrating
Combined Modality Therapy
Decision Making
Europe
Female
Geriatric Assessment
Humans
Male
Middle Aged
Neoplasm Metastasis
Neoplasm Staging
Practice Guidelines as Topic
Societies, Medical

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22469125