Corelation between cytologic, colposcopic and pathohistological findings of cervical intraepithelial lesions.
AIM OF THIS STUDY was to examine the frequency of cervical cancer and cervical intraepithelial lesions of a different degree
in women, corelation between cytologically diagnosed CIN I, CIN II and CIN III lesions and colposcopic findings and corelation
between cytologic and pathohistologic findings of CIN III lesion.
MATERIAL AND METHODS
Cytologic and colposcopic findings have been analysed retrospectively in 2652 women who went through systematic examinations in Women's Health Care Department at Health Center "Dr.Mustafa Sehovic" Tuzla in period 2008-2011. For 93.2% (N = 2475) cytology results were normal. Abnormal cytology result was found in 6.71% (N = 178): CIN I in 5.54% (147), CIN II in 0.67% (18) and CIN III in 0.49% (13) of women examined.
RESULTS AND DISCUSSION
Colposcopy in women with cytology results CIN I, CIN II and CIN III showed abnormal result in women with CIN I in 29.9% (44/147), CIN II in 61.1% (11/18) and CIN III in 61.5% (8/13). Significant association between abnormal colposcopic and abnormal cytologic findings (Chi2 = 36.30, p < 0.0005). Abnormal colposcopic result is twice as often with CIN II and CIN III changes on cervix in relation to CIN I. Byopsy of cervix in 13 women with CIN III pathohistologicaly confirmed the diagnose in 46.1% (4/13), cervix lesion was of higher degree in 30.8%, and in 23.0% (3/13) lesion of cervix was of a lower degree. Abnormal colposcopic image is an indicator for the abnormal cytological result.
Systematic examination of women represents an efficient way of organized screening and prevention of cervical cancer.
SourceMedicinski arhiv 66:2 2012 pg 122-4
Cervical Intraepithelial Neoplasia
Uterine Cervical Neoplasms
Pub Type(s)Journal Article