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Fatal Rocky Mountain spotted fever in the United States, 1999-2007.

Abstract

Death from Rocky Mountain spotted fever (RMSF) is preventable with prompt, appropriate treatment. Data from two independent sources were analyzed to estimate the burden of fatal RMSF and identify risk factors for fatal RMSF in the United States during 1999-2007. Despite increased reporting of RMSF cases to the Centers for Disease Control and Prevention, no significant changes in the estimated number of annual fatal RMSF cases were found. American Indians were at higher risk of fatal RMSF relative to whites (relative risk [RR] = 3.9), and children 5-9 years of age (RR = 6.0) and adults ≥ 70 years of age (RR = 3.0) were also at increased risk relative to other ages. Persons with cases of RMSF with an immunosuppressive condition were at increased risk of death (RR = 4.4). Delaying treatment of RMSF was also associated with increased deaths. These results may indicate a gap between recommendations and practice.

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  • Publisher Full Text
  • Authors

    Dahlgren FS, Holman RC, Paddock CD, Callinan LS, McQuiston JH

    Institution

    Rickettsial Zoonoses Branch, Division of Vectorborne Infectious Diseases, National Center for Emerging and Zoonotic Infectious Disease, Atlanta, Georgia, USA. iot0@cdc.gov

    Source

    The American journal of tropical medicine and hygiene 86:4 2012 Apr pg 713-9

    MeSH

    Adolescent
    Adult
    Aged
    Centers for Disease Control and Prevention (U.S.)
    Child
    Child, Preschool
    Female
    Humans
    Immunosuppressive Agents
    Incidence
    Indians, North American
    Infant
    Male
    Middle Aged
    Population Surveillance
    Risk Factors
    Rocky Mountain Spotted Fever
    United States
    Young Adult

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    22492159