Genetic diversity of Streptococcus equi subsp. zooepidemicus and doxycycline resistance in kennelled dogs.
Abstract
The genetic diversity and antibiotic resistance profiles of 38 Streptococcus equi subsp. zooepidemicus isolates were determined from a kennelled canine population during two outbreaks of hemorrhagic pneumonia (1999 to 2002 and 2007 to 2010). Analysis of the szp gene hypervariable region and the 16S-23S rRNA intergenic spacer region and multilocus sequence typing (MLST) indicated a predominant tetO-positive, doxycycline-resistant ST-10 strain during 1999 to 2002 and a predominant tetM-positive doxycycline-resistant ST-62 strain during 2007 to 2010.
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Authors
Chalker VJ, Waller A, Webb K, Spearing E, Crosse P, Brownlie J, Erles K
Institution
The Royal Veterinary College, Department of Pathology and Infectious Diseases, Hatfield, United Kingdom.
Source
Journal of clinical microbiology 50:6 2012 Jun pg 2134-6MeSH
AnimalsAnti-Bacterial Agents
Antigens, Bacterial
Bacterial Proteins
DNA, Ribosomal Spacer
Disease Outbreaks
Dog Diseases
Dogs
Doxycycline
Drug Resistance, Bacterial
Genetic Variation
Microbial Sensitivity Tests
Multilocus Sequence Typing
Pneumonia, Bacterial
Streptococcal Infections
Streptococcus equi
Pub Type(s)
Journal ArticleResearch Support, Non-U.S. Gov't
Language
eng
PubMed ID
22495558
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