Abstract

Bioadhesion refers to the phenomenon where natural and synthetic materials adhere to biological surfaces. An understanding of the fundamental mechanisms that govern bioadhesion is of great interest for various researchers who aim to develop new biomaterials, therapies and technological applications such as biosensors. This review paper will first describe various examples of the manifestation of bioadhesion along with the underlying mechanisms. This will be followed by a discussion of some of the methods for the optimization of bioadhesion. Finally, nanoscale and macroscale characterization techniques for the efficacy of bioadhesion and the analysis of failure surfaces are described.

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Publisher Full Text

Authors

Palacio ML, Bhushan B

Institution

Nanoprobe Laboratory for Bio- and Nanotechnology and Biomimetics, The Ohio State University, Columbus, 43210, USA. palacio.1@osu.edu

Source

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 370:1967 2012 May 28 pg 2321-47

MeSH

Biocompatible Materials
Biofilms
Cell Adhesion
Humans
Surface Properties

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22509061