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Mucosal fixed drug eruption in a patient treated with ornidazole.

Abstract

BACKGROUND
Therapeutic drugs have been observed to cause a wide spectrum of adverse oral effects such as dry mouth, gingival enlargement, taste disturbance, oral mucosal ulceration, halitosis, etc.
OBSERVATIONS
A rare case of intra-oral fixed drug eruption (FDE) induced by ornidazole presenting on the hard palate, an extremely rare site for FDE, in a 40-year-old male is reported.
CONCLUSIONS
Ornidazole is a relatively newer 5-nitroimidazole derivative commonly prescribed for Amoebic dysentery in developing countries. FDE is a rare adverse drug effect characterized by onset of round/oval, erythematous macules on the skin or mucosa that can be associated with itching and burning sensation. The exact mechanism causing FDE is unknown.

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    • Authors

    Marya CM, Sharma G, Parashar VP, Dahiya V

    Institution

    Department of Public Health Dentistry, Sudha Rustagi College of Dental Sciences & Research, Faridabad, Haryana, India.

    Source

    Journal of dermatological case reports 6:1 2012 Mar 27 pg 21-4

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    22514586