Unbound MEDLINE

Subcellular distribution of CdSe quantum dots (QDs) in breast cancer cells.

Abstract

In spite of great advances in conventional cancer diagnosis and treatment, the early recognition and characterization for various cancers remain a technological bottleneck. The combined characteristics of board absorption and narrow emission make quantum dots (QDs) desirable fluorescent labels for cancer imaging and other applications in the biomedical field. In the current study, to the best of our knowledge, we first evidenced the preferential accumulation of QDs in cytoplasm of breast cancer cells. QDs therefore reveal considerable potentials in both tumor imaging and therapeutic application.

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  • Publisher Full Text
  • Authors

    Hong L, Wang Z, Yuan L, Tan J, Wang L, Qu G, Zhang D, Lin R, Liu S

    Institution

    State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.

    Source

    Journal of nanoscience and nanotechnology 12:1 2012 Jan pg 365-7

    MeSH

    Breast Neoplasms
    Cadmium Compounds
    Cell Line, Tumor
    Diffusion
    Humans
    Quantum Dots
    Selenium Compounds
    Subcellular Fractions

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    22523988