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A cross-national comparative study of metabolic syndrome among non-diabetic Dutch and English ethnic groups.

Abstract

BACKGROUND
Evidence suggests a higher prevalence of type 2 diabetes (T2D) in The Netherlands than in England, although generalized obesity prevalence is substantially lower in The Netherlands. Metabolic syndrome (MS) is more strongly associated with the risk of progression to T2D than generalized obesity. Therefore examining MS may help to better understand the differences in T2D between the two countries. We assessed whether the Dutch and English differences in T2D prevalence reflect similar differences in MS in Whites, South-Asian Indians and African-Caribbeans living in these two countries.
METHODS
Secondary analyses of population-based studies of 3010 participants aged 35-60 years. Metabolic syndrome was defined according to the International Diabetes Federation criteria. Prevalence ratios (PRs) were estimated using regression models.
RESULTS
In general, the Dutch ethnic groups had a higher prevalence of MS than their English counterparts. Adjusted PRs were 1.37[95% confidence interval (CI)1.03-1.82] and 1.52 (1.06-2.19) in White-Dutch men and women compared to White-English men and women; 2.20 (1.14-4.26) and 1.46 (0.96-2.24) in Dutch-African-Caribbean men and women compared to English-African-Caribbean men and women and 0.97 (0.74-1.27) and 1.42 (1.00-2.03) in Dutch-Indian men and women compared with their English-Indian peers, respectively. Similar patterns were also observed for some MS components, e.g. raised fasting glucose in men and central obesity in women.
CONCLUSION
The comparatively high prevalence of MS among Dutch ethnic groups may contribute to their high prevalence of T2D. The high levels of some MS components, e.g. raised fasting glucose in men and central obesity in women add to the high prevalence of MS in Dutch ethnic groups.

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  • Authors

    Agyemang C

    Department of Public Health, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

    Kunst AE

    Bhopal R

    Zaninotto P

    Nazroo J

    Unwin N

    van Valkengoed I

    Redekop WK

    Stronks K

    Source

    European journal of public health 23:3 2013 Jun pg 447-52

    MeSH

    Adult
    Africa
    African Continental Ancestry Group
    Anthropometry
    Blood Glucose
    Cardiovascular Diseases
    Cross-Cultural Comparison
    Cross-Sectional Studies
    Diabetes Mellitus, Type 2
    England
    Ethnic Groups
    European Continental Ancestry Group
    Female
    Health Surveys
    Humans
    Hypertension
    India
    Life Style
    Lipids
    Male
    Metabolic Syndrome X
    Middle Aged
    Netherlands
    Obesity
    Population Surveillance
    Regression Analysis
    Risk Factors
    Socioeconomic Factors

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    22542542