Unbound MEDLINE

Suture type and ultrasound-indicated cerclage efficacy.

Abstract

OBJECTIVE
To assess whether type of suture material affects cerclage efficacy for preterm birth (PTB) prevention.
METHODS
Secondary analysis of a multicenter trial of ultrasound-indicated cerclage for short cervical length (CL), in which women with prior spontaneous PTB at 16-33 6/7 weeks, a singleton gestation and CL < 25 mm between 16-22 6/7 weeks, were randomized to McDonald cerclage or no cerclage. Outcomes of women who underwent cerclage were analyzed by type of suture material, comparing polyester braided thread (Mersilene™ or Ethibond™) to Mersilene tape™. Primary outcome was PTB < 35 weeks.
RESULTS
138 women underwent McDonald cerclage: 84 (61%) received polyester braided thread and 46 (33%) Mersilene tape™. Eight (6%) received monofilament suture and were excluded from analysis. Rates of PTB < 35 weeks were similar, 35% for polyester braided thread vs 24% for Mersilene tape™ (p = .24). Birth gestational age was also similar among the 2 groups (p = .18).
CONCLUSION
Type of suture material may not affect ultrasound-indicated cerclage efficacy in high-risk women with short CL, but further study is needed. Polyester braided thread (Mersilene™ or Ethibond™) and polyester braided Mersilene tape™ seem to have similar efficacy.

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  • Publisher Full Text

    • Authors

    Berghella V, Szychowski JM, Owen J, Hankins G, Iams JD, Sheffield JS, Perez-Delboy A, Wing DA, Guzman ER, Vaginal Ultrasound Trial Consortium

    Institution

    Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA 19107, USA. vincenzo.berghella@jefferson.edu

    Source

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 25:11 2012 Nov pg 2287-90

    MeSH

    Adult
    Cerclage, Cervical
    Cervix Uteri
    Female
    Humans
    Pregnancy
    Premature Birth
    Suture Techniques
    Sutures
    Treatment Outcome
    Ultrasonography, Interventional
    Ultrasonography, Prenatal
    Uterine Cervical Incompetence
    Young Adult

    Pub Type(s)

    Journal Article
    Multicenter Study
    Randomized Controlled Trial
    Research Support, N.I.H., Extramural

    Language

    eng

    PubMed ID

    22545593