Unbound MEDLINE

Clinical evaluation of intensity-modulated radiotherapy for head and neck cancers.

Abstract

Radiotherapy and surgery are the principal curative modalities in treatment of head and neck cancer. Conventional two-dimensional and three-dimensional conformal radiotherapy result in significant side effects and altered quality of life. Intensity-modulated radiotherapy (IMRT) can spare the normal tissues, while delivering a curative dose to the tumour-bearing tissues. This article reviews the current role of IMRT in head and neck cancer from the point of view of normal tissue sparing, and also reviews the current published literature by individual head and neck cancer subsites. In addition, we briefly discuss the role of image guidance in head and neck IMRT, and future directions in this area.

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  • Publisher Full Text
  • Authors

    Bhide SA, Newbold KL, Harrington KJ, Nutting CM

    Institution

    Head and Neck Unit, Royal Marsden Hospital, Sutton, Surrey, UK.

    Source

    The British journal of radiology 85:1013 2012 May pg 487-94

    MeSH

    Carcinoma, Squamous Cell
    Deglutition Disorders
    Head and Neck Neoplasms
    Humans
    Hypopharyngeal Neoplasms
    Laryngeal Neoplasms
    Nasopharyngeal Neoplasms
    Oropharyngeal Neoplasms
    Paranasal Sinus Neoplasms
    Parotid Gland
    Parotid Neoplasms
    Radiation Oncology
    Radiotherapy Planning, Computer-Assisted
    Radiotherapy, Intensity-Modulated
    Thyroid Neoplasms

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    22556403