Antibacterial activity of ammonium hexafluorosilicate solution with antimicrobial agents for the prevention of dentin caries.
This study evaluated the antibacterial activity of the SiF solution with the addition of antibacterial agents on a Streptococcus mutans biofilm.
Various antibacterial SiF solutions were prepared by adding chlorhexidine, cetylpyridinium chloride, isopropyl methylphenol, or epigallocatechin gallate. Hydroxyapatite pellets treated with several SiF solutions were immersed in BHI inoculated with S. mutans standardized suspension. The number of S. mutans cells adhered to each pellet was evaluated.
SiF with the addition of CPC was the most effective for reducing the adherence of bacteria and inhibiting the formation ofbiofilm, showing the same level as AgF, In contrast, the addition of other antibacterial agents to SiF reduced the original antibacterial activity of SiF solution.
Department of Conservative Dentistry, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.
SourceAmerican journal of dentistry 25:1 2012 Feb pg 31-4
MeSHAcid Etching, Dental
Anti-Infective Agents, Local
Microscopy, Electron, Scanning
Pub Type(s)Journal Article
Research Support, Non-U.S. Gov't