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Irritable bowel syndrome, gastro-oesophageal reflux disease and dyspepsia: overlap analysis using loglinear models.

Abstract

BACKGROUND AND STUDY AIMS
Irritable bowel syndrome (IBS), gastro-oesophageal reflux disease (GERD) and dyspepsia are three most important gastrointestinal disorders which occur frequently together in patients. This study aims to assess the association between IBS, GERD and dyspepsia by using loglinear model analysis.
PATIENTS AND METHODS
This cross-sectional household survey, the purpose of which was to find the prevalence of gastrointestinal symptoms, disorders and the related factors, has been done from May 2006 to December 2007 in Tehran province, Iran. Subjects were interviewed by trained personnel. GERD was diagnosed as the experience of heartburn and/or acid regurgitation at least once a week for the last 3 months. IBS and dyspepsia were diagnosed according to the Rome III criteria. Loglinear models were applied to investigate the simultaneous association between IBS, GERD and dyspepsia.
RESULTS
77.9% of IBS patients had dyspepsia symptoms and 74.7% had GERD symptoms as well at the same time. As for the other two symptoms, 66% of GERD patients were also suffering from dyspepsia.
CONCLUSIONS
These three symptoms frequently overlap; the overlap is systematic and not by chance or random.

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  • Publisher Full Text
  • Authors

    Pourhoseingholi A, Vahedi M, Pourhoseingholi MA, Ashtari S, Moghimi-Dehkordi B, Safaee A, Zali MR

    Institution

    Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Science, Tehran, Iran.

    Source

    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 13:1 2012 Mar pg 20-3

    MeSH

    Adult
    Cross-Sectional Studies
    Dyspepsia
    Female
    Gastroesophageal Reflux
    Health Surveys
    Humans
    Iran
    Irritable Bowel Syndrome
    Linear Models
    Male
    Middle Aged
    Prevalence
    Questionnaires

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    22560820