Irritable bowel syndrome, gastro-oesophageal reflux disease and dyspepsia: overlap analysis using loglinear models.
Abstract
BACKGROUND AND STUDY AIMS
Irritable bowel syndrome (IBS), gastro-oesophageal reflux disease (GERD) and dyspepsia are three most important gastrointestinal
disorders which occur frequently together in patients. This study aims to assess the association between IBS, GERD and dyspepsia
by using loglinear model analysis.
PATIENTS AND METHODS
This cross-sectional household survey, the purpose of which was to find the prevalence of gastrointestinal symptoms, disorders
and the related factors, has been done from May 2006 to December 2007 in Tehran province, Iran. Subjects were interviewed
by trained personnel. GERD was diagnosed as the experience of heartburn and/or acid regurgitation at least once a week for
the last 3 months. IBS and dyspepsia were diagnosed according to the Rome III criteria. Loglinear models were applied to investigate
the simultaneous association between IBS, GERD and dyspepsia.
RESULTS
77.9% of IBS patients had dyspepsia symptoms and 74.7% had GERD symptoms as well at the same time. As for the other two symptoms,
66% of GERD patients were also suffering from dyspepsia.
CONCLUSIONS
These three symptoms frequently overlap; the overlap is systematic and not by chance or random.
Links
Authors
Pourhoseingholi A, Vahedi M, Pourhoseingholi MA, Ashtari S, Moghimi-Dehkordi B, Safaee A, Zali MR
Institution
Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Science, Tehran, Iran.
Source
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 13:1 2012 Mar pg 20-3MeSH
AdultCross-Sectional Studies
Dyspepsia
Female
Gastroesophageal Reflux
Health Surveys
Humans
Iran
Irritable Bowel Syndrome
Linear Models
Male
Middle Aged
Prevalence
Questionnaires
Pub Type(s)
Journal ArticleResearch Support, Non-U.S. Gov't
Language
eng
PubMed ID
22560820
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