Abstract

BACKGROUND
Heart rate variability (HRV) is an useful noninvasive tool to assess autonomic nervous system (ANS) function and may provide an insight into the understanding of the role of ANS in the pathogenesis of blood pressure (BP) abnormality in euvolemic continuous ambulatory peritoneal dialysis (CAPD) patients.
METHODS
In this cross-sectional study, 62 CAPD patients with normal hydration values (assessed by a bioimpedance spectroscopy device) were enrolled from our peritoneal dialysis (PD) unit. Patients were divided into three groups according to their BP: normotension (NT), hypertension (HT), and hypotension (HyT). Spectral analysis of HRV was measured by examination of the average heart rate using standard electrocardiogram in 5 min.
RESULTS
The HyT group had the lowest serum urea nitrogen among the three groups (all p < 0.05), and a lower serum potassium and albumin as compared with the NT group (p < 0.05). The HyT group also had the highest total power (TP) and highest frequency power (HF) among the three groups (all p < 0.05), and a lower normalized low frequency power (LF), LF/HF ratio, and a higher normalized HF as compared with the HT group (all p < 0.05).
CONCLUSION
Our study suggested that autonomic insufficiency was present in euvolemic PD patients, and hypotensives had a relatively higher parasympathetic activity and blunted sympathetic activity.

Links

Publisher Full Text

Authors

Pei J, Tang W, Li LX, Su CY, Wang T

Institution

Division of Nephrology, Peking University Third Hospital, Beijing, PR China.

Source

Renal failure 34:6 2012 pg 722-6

MeSH

Albumins
Analysis of Variance
Autonomic Nervous System
Biological Markers
Chi-Square Distribution
Cross-Sectional Studies
Electric Impedance
Electrocardiography
Female
Heart Rate
Humans
Hypertension
Hypotension
Kidney Diseases
Male
Middle Aged
Nitrogen
Peritoneal Dialysis
Potassium
Serum Albumin

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22571592