Prevalence and clinical correlates of early repolarization and J wave in a large cohort of subjects without overt heart disease.
Abstract
BACKGROUND
Recent studies have suggested that early repolarization (ER) is associated with increased risk of ventricular tachyarrhythmias.
Early repolarization in these studies, however, was defined as J-wave (terminal QRS slurring or notching) or J-point elevation
rather than typical ST-segment elevation (STE). Prevalence and characteristics of these different findings in the general
population are poorly known. In this study, we assessed prevalence and correlates of STE typical of ER and of J wave in a
large population of noncardiac subjects.
METHODS
We prospectively collected electrocardiograms of 4176 consecutive subjects without heart disease at our hospital.
RESULTS
Early repolarization was found in 84 subjects (2.0%) and J wave in 663 (15.9%). Among ER subjects, a J wave was present in
60 (71.4%). Variables independently associated with both ER and J wave included young age, male sex, and lower heart rate.
There was no increased history of symptoms (palpitations and syncope) possibly related to arrhythmias in STE or J-wave subjects.
CONCLUSIONS
Typical ER pattern and J wave are common in noncardiac subjects, particularly in young people, and are not associated with
symptoms potentially related to arrhythmias.
Links
Authors
Lanza GA, Mollo R, Cosenza A, Pinnacchio G, Careri G, Laurito M, Crea F
Institution
Dipartimento di Medicina Cardiovascolare, Università Cattolica del Sacro Cuore, Rome, Italy. g.a.lanza@rm.unicatt.it
Source
Journal of electrocardiology 45:4 pg 404-10MeSH
AdultAged
Aged, 80 and over
Electrocardiography
Female
Heart Conduction System
Heart Rate
Humans
Male
Middle Aged
Pub Type(s)
Journal ArticleLanguage
eng
PubMed ID
22575808
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