Abstract

We aimed to test a new model of self-expanding tracheal stent so that it might be made available for clinical use. Using direct laryngoscopy, we placed polyurethane-coated, nitinol stents into the middle third of the trachea in 25 New Zealand rabbits. After a mean observation period of 26 days, we evaluated stent migration, degree of expansion, attachment, adherence, formation of granulation tissue, presence of inflammatory infiltrate, parietal involvement, and epithelial lining. The results showed complete radial expansion, little adherence to the tracheal mucosa, and low tissue attachment, as well as high rates of granuloma formation and stent migration. This new model proved to be biocompatible and showed a behavior similar to that of other stents on the market.

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Publisher Full Text

Authors

Faria CM, Rodrigues OR, Minamoto H, Cury PM, Costa Neto Jde M, Braile DM

Institution

São José do Rio Preto School of Medicine, São José do Rio Preto, Rua Alcides Rossani 853, Vilage LaMontagne, São José do Rio Preto, SP, Brazil. fariamurilo@hotmail.com

Source

Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia 38:2 2012 Apr pg 214-7

MeSH

Alloys
Animals
Brazil
Coated Materials, Biocompatible
Polyurethanes
Prosthesis Design
Rabbits
Stents
Tracheal Stenosis

Pub Type(s)

Evaluation Studies
Journal Article

Language

eng por

PubMed ID

22576430