Abstract

OBJECTIVE
To evaluate the magnitude of diurnal changes in the parameters of pulmonary function and respiratory muscle strength/endurance in a sample of patients with COPD.
METHODS
A group of 7 patients underwent spirometry, together with determination of MIP and MEP, at two distinct times (between 8:00 and 8:30 a.m. and between 4:30 and 5:00 p.m.) on a single day. Between assessments, the patients remained at rest in the laboratory.
RESULTS
In accordance with the Global Initiative for Chronic Obstructive Pulmonary Disease staging system, COPD was classified as moderate, severe, and very severe in 1, 3, and 3 of the patients, respectively. From the first to the second assessment, there were significant decreases in FVC, FEV1, and MEP (of 13%, 15%, and 10%, respectively), as well as (less than significant) decreases in PEF, MIP, and maximal voluntary ventilation (of 9%, 3%, and 11%, respectively).
CONCLUSIONS
In this sample of COPD patients, there were diurnal variations in the parameters of pulmonary function and respiratory muscle strength. The values of FEV1, FVC, and MEP were significantly lower in the afternoon than in the morning.

Links

Publisher Full Text

Authors

Fregonezi G, Resqueti VR, Cury JL, Paulin E, Brunetto AF

Institution

Laboratory of Respiratory Physical Therapy, Department of Physical Therapy, Regional University Hospital of Northern Paraná, State University at Londrina, Londrina, Brazil. fregonezi@ufrnet.br

Source

Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia 38:2 2012 Apr pg 257-63

MeSH

Aged
Circadian Rhythm
Female
Humans
Male
Middle Aged
Muscle Strength
Pulmonary Disease, Chronic Obstructive
Respiratory Function Tests
Respiratory Muscles
Severity of Illness Index
Spirometry

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng por

PubMed ID

22576435