Abstract

Cutaneous involvement by an eosinophil-rich process (eosinophilic dermatosis) may be encountered in the setting of various hematologic malignancies, including mantle cell lymphoma, acute monocytic leukemia, acute lymphoblastic leukemia, large cell lymphoma, myelofibrosis and chronic lymphocytic leukemia (CLL). Of the various hematologic malignancies, eosinophilic dermatosis has been most frequently described in association with CLL. Published previously as insect bite-like reaction and eosinophilic dermatosis of myeloproliferative disease, this rare dermatitis presents as a pruritic, papular and occasionally vesicular eruption associated with an eosinophil-rich infiltrate histopathologically. Although clinical and histopathologic features are similar to insect bites, affected patients frequently deny a history of insect bites. We report a case of eosinophilic dermatosis of hematologic malignancy in a patient with known history of CLL.

Links

Publisher Full Text

Authors

Farber MJ, La Forgia S, Sahu J, Lee JB

Institution

Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Source

Journal of cutaneous pathology 39:7 2012 Jul pg 690-5

MeSH

Aged
Eosinophils
Humans
Leukemia, Lymphocytic, Chronic, B-Cell
Male
Skin Diseases
Skin Neoplasms

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22612903