Abstract

These Guidelines summarize and evaluate all currently available evidence on Acute Myocardial Infarction (AMI) with the aim of assisting physicians in selecting the best management strategies for a typical patient, suffering from AMI, taking into account the impact on outcome, as well as the risk/benefit ratio of particular diagnostic or therapeutic means. Rapid diagnosis and early risk stratification of patients presenting with AMI are important to identify patients in whom early interventions can improve outcome. AMI can be defined from a number of different perspectives related to clinical, electrocardiographic (ECG), biochemical, and pathological characteristics. Quantitative assessment of risk is useful for clinical decision making. For patients with the clinical presentation of AMI within 12 h after symptom onset, early mechanical (PCI) or pharmacological reperfusion should be performed. Platelet activation and subsequent aggregation play a dominant role in the propagation of arterial thrombosis and consequently are the key therapeutic targets in the management of AMI. Adjunctive therapy with antiplatelets and antithrombotics is essential. A recommendation for routine urgent PCI (within 24 h) following successful fibrinolysis seems to be most practical option. In India, pharmacoinvasive therapy is the best option.

Authors

Banerjee AK, Kumar S

Institution

AMRI Hospital, Salt Lake, Kolkata.

Source

The Journal of the Association of Physicians of India 59 Suppl: 2011 Dec pg 37-42

MeSH

Angioplasty, Balloon, Coronary
Disease Management
Echocardiography
Electrocardiography
Evidence-Based Medicine
Fibrinolytic Agents
Humans
India
Myocardial Infarction
Myocardial Reperfusion
Practice Guidelines as Topic
Risk Assessment
Risk Factors
Thrombolytic Therapy
Time Factors
Treatment Outcome

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22624280